課程名稱 |
微生物基因調控與表達特論 Special Topics in Microbial Gene Regulation and Expression |
開課學期 |
100-1 |
授課對象 |
生物資源暨農學院 生物科技研究所 |
授課教師 |
劉?睿 |
課號 |
Biot8018 |
課程識別碼 |
642ED0200 |
班次 |
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學分 |
3 |
全/半年 |
半年 |
必/選修 |
選修 |
上課時間 |
星期三5,6,7(12:20~15:10) |
上課地點 |
生技所415 |
備註 |
本課程以英語授課。 限博士班 總人數上限:10人 |
Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1001MicrobialGene |
課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
課程大綱
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課程概述 |
This course will cover the gene structure and the expression of genes in microbial systems. The structure of polycistronic operons, the regulation of expression, induction and repression, translational control, integration of expression with metabolic pathways will also be covered. |
課程目標 |
The principles of this course are to provide a critical evaluation of the current state of knowledge concerning microbial gene regulation and expression. |
課程要求 |
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
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參考書目 |
1. Moat, A. G., J. W. Foster, and M. P. Spector. 2002. Microbial Physiology. Wiley-Liss, New York, USA.
2. Lee, Y. K. 2003. Microbial Biotechnology: Principles and Applications. World Scientific Publishing Company, Singapore. |
評量方式 (僅供參考) |
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週次 |
日期 |
單元主題 |
第1週 |
9/14 |
Introduction |
第2週 |
9/21 |
Principles of microbial biotechnology |
第3週 |
9/28 |
Production of recombinant proteins by Escherichia coli |
第4週 |
10/05 |
Production of recombinant proteins by Gram-positive Bacteria |
第5週 |
10/12 |
Production of recombinant proteins by Pseudomonas fluorescens |
第6週 |
10/19 |
Production of recombinant proteins by Arxula adeninivorans |
第7週 |
10/26 |
Ruminal Microbiology and Production of recombinant proteins by Pichia pastoris |
第8週 |
11/02 |
Production of recombinant proteins by Aspergillus |
第9週 |
11/09 |
Midterm examination |
第10週 |
11/16 |
Biogas from microbial fermentation |
第11週 |
11/23 |
Biodegradable plastic |
第12週 |
11/30 |
Help crops grow in harsh environments |
第13週 |
12/07 |
Using microbial 2nd metabolites as a source of drug |
第14週 |
12/14 |
Control of pathogenic microbes |
第15週 |
12/21 |
Resistance to viral diseases(RNA silencing) |
第16週 |
12/28 |
Modern microbial biotechnology agenda: presentations and colloquial discussions |
第17週 |
1/04 |
Terminal examination |
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